| 货号 | 65699S |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human |
| 应用 | F |
| 目标/特异性 | NY-ESO-1 (D1Q2U) Rabbit mAb (PE Conjugate) recognizes endogenous levels of total NY-ESO-1 protein. This antibody cross-reacts with NY-ESO-2/LAGE-1S. |
| 使用方法 | Flow Cytometry (1:50) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Cancer/testis antigens (CTAs) are a family of more than 100 proteins whose normal expression is largely restricted to immune privileged germ cells of the testis, ovary, and trophoblast cells of the placenta. Although most normal somatic tissues are void of CTA expression, due to epigenetic silencing of gene expression, their expression is upregulated in a wide variety of human solid and liquid tumors (1,2). As such, CTAs have garnered much attention as attractive targets for a variety of immunotherapy-based approaches to selectively attack tumors (3). |
| 存放说明 | 4C |
| 参考文献 | 1 . Caballero, O.L. and Chen, Y.T. (2009) Cancer Sci 100, 2014-21. 2 . De Smet, C. et al. (1999) Mol Cell Biol 19, 7327-35. 3 . Gjerstorff, M.F. et al. (2015) Oncotarget 6, 15772-87. |
Flow cytometric analysis of Jurkat cells (blue) and U266 cells (green) using NY-ESO-1 (D1Q2U) Rabbit mAb (PE Conjugate). |
