COX IV (3E11) Rabbit mAb (Alexa Fluor® 555 Conjugate)
货号：
8693S 基本售价：
4060.0 元 规格：
-
产品信息
概述| 货号 | 8693S |
| 描述 | This Cell Signaling Technology (CST) antibody is conjugated to Alexa Fluor® 555 fluorescent dye under optimal conditions and tested in-house for direct immunofluorescent analysis in human cells. This antibody is expected to exhibit the same species cross-reactivity as the unconjugated COX IV (3E11) Rabbit mAb #4850. |
| 反应种属 | Human/Rat/Monkey/ZebrafishBovine/Pig |
| 来源宿主 | Rabbit |
| 应用 | IF-IC |
| 目标/特异性 | COX IV (3E11) Rabbit mAb (Alexa Fluor® 555 Conjugate) detects endogenous levels of total COX IV protein. |
| 使用方法 | IF-IC(1:50) |
性能| 供应商 | CST |
| 标记 | Alexa Fluor 555 |
| 背景 | Cytochrome c oxidase (COX) is a hetero-oligomeric enzyme consisting of 13 subunits localized to the inner mitochondrial membrane (1-3). It is the terminal enzyme complex in the respiratory chain, catalyzing the reduction of molecular oxygen to water coupled to the translocation of protons across the mitochondrial inner membrane to drive ATP synthesis. The 3 largest subunits forming the catalytic core are encoded by mitochondrial DNA while the other smaller subunits, including COX IV, are nuclear-encoded. Research studies have shown that deficiency in COX activity correlates with a number of human diseases (4). The COX IV antibody can be used effectively as a mitochondrial loading control in cell-based research assays. |
| 存放说明 | 4C |
参考图片Confocal immunofluorescent analysis of HeLa cells using COX IV (3E11) Rabbit mAb (Alexa Fluor® 555 Conjugate) (red). Actin filaments were labeled with Alexa Fluor® 488 phalloidin (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). 对HeLa细胞使用COX IV (3E11) Rabbit mAb兔单抗 (Alexa Fluor? 555 Conjugate)（红色）进行共聚焦免疫荧光分析。肌动蛋白用Alexa Fluor? 488 phalloidin（绿色）标记。蓝色伪彩=DRAQ5?#4084(荧光DNA染料)。 |
