COX IV (3E11) Rabbit mAb (HRP Conjugate)
货号:
5247S 基本售价:
4060.0 元 规格:
-
产品信息
概述货号 | 5247S |
描述 | This Cell Signaling Technology (CST) antibody is conjugated to the carbohydrate groups of horseradish peroxidase (HRP) via its amine groups. The HRP conjugated antibody is expected to exhibit the same species cross-reactivity as the unconjugated antibody (COX IV (3E11) Rabbit mAb #4850). |
反应种属 | Human/Rat/Monkey/ZebrafishBovine/Pig |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | COX IV (3E11) Rabbit mAb (HRP Conjugate) detects endogenous levels of total COX IV protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
标记 | HRP |
背景 | Cytochrome c oxidase (COX) is a hetero-oligomeric enzyme consisting of 13 subunits localized to the inner mitochondrial membrane (1-3). It is the terminal enzyme complex in the respiratory chain, catalyzing the reduction of molecular oxygen to water coupled to the translocation of protons across the mitochondrial inner membrane to drive ATP synthesis. The 3 largest subunits forming the catalytic core are encoded by mitochondrial DNA while the other smaller subunits, including COX IV, are nuclear-encoded. Deficiency in COX activity has been correlated with a number of human diseases (4). The COX IV antibody can be used effectively as a mitochondrial loading control. |
存放说明 | -20C |
计算分子量 | 17 |
参考图片Western blot analysis of extracts from Jurkat, HeLa and COS cell lines, using COX IV (3E11) Rabbit mAb (HRP Conjugate). Wetern blot检测Jurkat, HeLa and COS细胞系提取物,所用抗体为COX IV (3E11) Rabbit mAb兔单抗 (HRP Conjugate)。 |