GFAP (GA5) Mouse mAb (Alexa Fluor® 647 Conjugate)
货号：
3657S 基本售价：
4060.0 元 规格：
-
产品信息
概述| 货号 | 3657S |
| 描述 | This Cell Signaling Technology antibody is conjugated to Alexa Fluor® 647 fluorescent dye and tested in-house for direct immunofluorescence of rat cells. The unconjugated antibody #3670 reacts with human, mouse and rat GFAP protein. CST expects that GFAP (GA5) Mouse mAb (Alexa Fluor® 647 Conjugate) will also recognize GFAP in these species. |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Mouse |
| 应用 | IF-F |
| 目标/特异性 | GFAP (GA5) Mouse mAb (Alexa Fluor® 647 Conjugate) detects endogenous levels of total GFAP protein. |
| 使用方法 | IF-F(1:50) |
性能| 供应商 | CST |
| 标记 | Alexa Fluor 647 |
| 背景 | The cytoskeleton consists of three types of cytosolic fibers: microfilaments (actin filaments), intermediate filaments and microtubules. Major types of intermediate filaments are specifically expressed in particular cell types: cytokeratins in epithelial cells, glial fibrillary acidic protein (GFAP) in glial cells, desmin in skeletal, visceral and certain vascular smooth muscle cells, vimentin in cells of mesenchymal origin and neurofilaments in neurons. GFAP and vimentin form intermediate filaments in astroglial cells and modulate their motility and shape (1). In particular, vimentin filaments are present at early developmental stages, while GFAP filaments are characteristic of differentiated and mature brain astrocytes. Thus, GFAP is commonly used as a marker for intracranial and intraspinal tumors arising from astrocytes (2). In addition, GFAP intermediate filaments are also present in non-myelin forming Schwann cells in the peripheral nervous system (3). |
| 存放说明 | 4C |
参考图片Confocal immunofluorescent analysis of rat brain using GFAP (GA5) Mouse mAb (Alexa Fluor® 647 Conjugate) (blue pseudocolor) and Neurofilament-L (DA2) Mouse mAb #2835 (green). 共聚焦免疫荧光分析大鼠大脑，使用的抗体是GFAP (GA5) Mouse mAb (Alexa Fluor® 647 Conjugate)（蓝色伪彩）和Neurofilament-L (DA2) Mouse mAb 鼠单抗 #2835（绿色）。 |
