IκBα (L35A5) Mouse mAb (Amino-terminal Antigen) (Biotinylated)
货号：
7543S 基本售价：
4060.0 元 规格：
-
产品信息
概述| 货号 | 7543S |
| 描述 | This Cell Signaling Technology antibody is conjugated to biotin under optimal conditions. The biotinylated antibody is expected to exhibit the same species cross-reactivity as the unconjugated IκBα (L35A5) Mouse mAb (Amino-terminal Antigen) #4814. |
| 反应种属 | Human/Mouse/Rat/Monkey/Bovine/Pig/GuineaPig |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | IκBα (L35A5) Mouse mAb (Amino-terminal Antigen) (Biotinylated) detects endogenous levels of total IκBα protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 标记 | Biotin |
| 背景 | The NF-κB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IκB proteins (1-3). Activation occurs via phosphorylation of IκBα at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-κB (3-7). IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. Kinases that phosphorylate IκB at these activating sites have been identified (8). |
| 存放说明 | -20C |
| 计算分子量 | 39 |
参考图片Western blot analysis of extracts from various cell lines using IκBα (L35A5) Mouse mAb (Amino-terminal Antigen) (Biotinylated). Streptavidin-HRP #3999 was used for detection.Western免疫印迹。用IκBα (L35A5) Mouse mAb (Amino-terminal Antigen) (Biotinylated)研究各种细胞系的细胞提取液。Streptavidin-HRP #3999 用于检测。 |
