NUP98 (C39A3) Rabbit mAb (Alexa Fluor® 647 Conjugate)
货号：
13393S 基本售价：
4060.0 元 规格：
-
产品信息
概述| 货号 | 13393S |
| 描述 | <p>This Cell Signaling Technology antibody is conjugated to Alexa Fluor<sup>®</sup> 647 fluorescent dye and tested in-house for direct immunofluorescent analysis in human cells. This antibody is expected to exhibit the same species cross-reactivity as the unconjugated NUP98 (C39A3) Rabbit mAb #2598.</p> Cell Signaling Technology抗体被Alexa Fluor® 647荧光染料标记，经过对人细胞免疫分析的内部试验验证。经证实抗体与未标记的NUP98 (C39A3) Rabbit mAb #2598有同样的反应性。 |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | IF-IC |
| 使用方法 | IF-IC(1:50) |
性能| 供应商 | CST |
| 标记 | Alexa Fluor 647 |
| 背景 | <p>Nucleoporin 98 kDa (NUP98) is a component of the nuclear pore complex. It is expressed as three different precursors that undergo auto-cleavage to generate a common amino-terminal 98 kDa peptide (NUP98) and carboxy-terminal 6, 96 (NUP96) and 88 (p88) kDa peptides (1,2). NUP98 contains FG and GLFG repeat domains at its amino terminus and a RNA-binding domain in its carboxy terminus (3). The NUP98 gene is localized on chromosome 11p15.5, a region frequently rearranged in leukemias. To date, 15 fusion partners have been identified for NUP98 (4,5).</p> Nucleoporin 98 kDa (NUP98)是细胞核孔复合物的一部分。会表达三个不同的前体再通过自剪切形成一个98kDa氨基末端肽段（NUP98）和6羧基端，96 (NUP96)和88（p88）kDa肽段（1,2）。NUP98在它的氨基末端含有FG和GLFG重复结构域，并在羧基端还有一个RNA结合结构域（3）。NUP98基因位于染色体的11p15.5,该区域在白血病中经常发生重排。迄今为止，NUP98共发现了15种融合配体（4,5）。 |
| 存放说明 | 4C |
参考图片Confocal immunofluorescent analysis of HeLa cells using NUP98 (C39A3) Rabbit mAb (Alex Fluor® 647 Conjugate) (blue pseudocolor). Actin filaments were labeled with DyLight™ 554 Phalloidin #13054 (red).使用NUP98 (C39A3) Rabbit mAb (Alex Fluor® 647 Conjugate)对HeLa细胞提取物进行激光共聚焦免疫荧光分析（蓝色假色）。肌动蛋白丝使用DyLight™ 554 Phalloidin #13054标记（红色）。 |
