Phospho-DDR1 (Tyr513) (E1N8F) Rabbit mAb
货号：
14531S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 14531S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The discoidin domain receptors (DDRs) are receptor tyrosine kinases with a discoidin homology repeat in their extracellular domains, activated by binding to extracellular matrix collagens. So far, two mammalian DDRs have been identified: DDR1 and DDR2 (1). They are widely expressed in human tissues and may have roles in smooth muscle cell-mediated collagen remodeling (2). Research studies have implicated aberrant expression and signaling of DDRs in human diseases related to increased matrix degradation and remodeling, such as cardiovascular disease, liver fibrosis, and tumor invasion (1). |
| 存放说明 | -20C |
| 计算分子量 | 125 |
参考图片Western blot analysis of extracts from T47-D cells, untreated (-) or treated with collagen (20 μg/ml, 18 hr; +), using Phospho-DDR1 (Tyr513) (E1N8F) Rabbit mAb (upper) and DDR1 (D1G6) XP® Rabbit mAb #5583 (lower). |
