Phospho-Jak3 (Tyr980/981) (D44E3) Rabbit mAb
货号：
5031S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 5031S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Phospho-Jak3 (Tyr980/981) (D44E3) Rabbit mAb detects endogenous levels of Jak3 when phosphorylated at Tyr980/981. Some reactivity may exist with single phosphorylation at these sites. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4) and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. |
| 存放说明 | -20C |
| 计算分子量 | 115 |
参考图片Western blot analysis of extracts from NK-92 cells, untreated or treated with Human Interleukin-2 (hIL-2) #8907 (10 ng/ml, 15 minutes), using Phospho-Jak3 (Tyr980/981) (D44E3) Rabbit mAb (upper) or Jak3 Antibody #3775 (lower).Western免疫印迹。用Phospho-Jak3 (Tyr980/981) (D44E3) Rabbit mAb (上图) 或 Jak3 Antibody #3775 (下图)研究未经处理的和经(hIL-2) #8907 (10 ng/ml, 15 min)处理的NK-92 细胞的细胞提取液。 |
