Phospho-MAPKAPK-2 (Thr222) (9A7) Rabbit mAb
货号：
3316S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 3316S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | In response to cytokines, stress and chemotactic factors, MAP kinase-activated protein kinase 2 (MAPKAPK-2) is rapidly phosphorylated and activated. It has been shown that MAPKAPK-2 is a direct target of p38 MAPK (1). Multiple residues of MAPKAPK-2 are phosphorylated in vivo in response to stress. However, only four residues (Thr25, Thr222, Ser272 and Thr334) are phosphorylated by p38 MAPK in an in vitro kinase assay (2). Phosphorylation at Thr222, Ser272 and Thr334 appears to be essential for the activity of MAPKAPK-2 (2). Thr25 is phosphorylated by p42 MAPK in vitro, but is not required for the activation of MAPKAPK-2 (2).Thr25 is phosphorylated by p42 MAPK in vitro, but is not required for the activation of MAPKAPK-2 (2). |
| 存放说明 | -20C |
| 计算分子量 | 49 |
参考图片Western blot analysis of extracts from HeLa cells, untreated (-) or UV- and TPA-treated (+), using Phospho-MAPKAPK-2 (Thr222) (9A7) Rabbit mAb (upper), or MAPKAPK-2 Antibody #3042 (lower).Western blot方法检测细胞提取物：未经处理的(-) 和紫外照射、TPA处理的(+)HeLa细胞，使用的抗体是Phospho-MAPKAPK-2 (Thr222) (9A7) Rabbit mAb (上图)和 MAPKAPK-2 Antibody #3042 (下图)。 |
