Phospho-SF3B1 (Thr313) (D8D8V) Rabbit mAb
货号：
25009S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 25009S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit IgG |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Phosphorylation of SF3B1 at Thr313 is only found in catalytically active spliceosomes and associates mainly with chromatin, where about 80% of pre-mRNA splicing occurs. Treatment with a transcription inhibitor 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole (DRB) leads to a decreased supply of pre-mRNA, resulting in the loss of phospho-SF3B1 (Thr313), consistent with its association with active splicing (7). |
| 存放说明 | -20C |
| 计算分子量 | 155 |
参考图片Western blot analysis of extracts from various cell lines using Phospho-SF3B1 (Thr313) (D8D8V) Rabbit mAb. |
Western blot analysis of extracts from HeLa cells, untreated (-) or treated with 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole (DRB) (+) using Phospho-SF3B1 (Thr313) (D8D8V) Rabbit mAb (upper) or SF3B1 (D7L5T) Rabbit mAb #14434 (lower). |
