| 货号 | 8664S |
| 反应种属 | Human/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Phospho-SGTA (Ser305) (D23E10) Rabbit mAb recognizes endogenous levels of SGTA protein only when phosphorylated at Ser305. |
| 使用方法 | WB(1:1000) IP (1:100) |
| 供应商 | CST |
| 背景 | SGTA, small glutamine-rich tetratricopeptide repeat-containing protein A, is an ubiquitously expressed co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (1,2). SGTA is a 34 kDa protein that is rich in glutamine residues at its C terminus and contains three tandemly repeated TPR motifs (3). The TPR domain of SGTA shows sequence similarity to the TPR domains of Hop, CHIP, and TOM70 (4). The TPR domain of SGTA also interacts with HSP90 and was recently found to be a pro-apoptotic factor (5,6). |
| 存放说明 | -20C |
| 计算分子量 | 34 |
Western blot analysis of extracts from HeLa cells, untreated (-) or treated with λ phosphatase (+), using Phospho-SGTA (Ser305) (D23E10) Rabbit mAb (upper) and SGTA Antibody #3349 (lower). 对未处理（-）或λ磷酸酶处理（+）的HeLa细胞提取物，使用Phospho-SGTA (Ser305) (D23E10) Rabbit mAb（上图）或SGTA Antibody #3349（下图）进行Western blot分析。 |
