Phospho-Thr-Pro-Arg Motif [pTPR] MultiMab™ Rabbit mAb mix
货号:
8142S 基本售价:
3980.0 元 规格:
-
产品信息
概述货号 | 8142S |
反应种属 | All |
来源宿主 | Rabbit IgG |
应用 | W |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | The MAPK and CDK families of serine/threonine protein kinases play important roles in proliferation and cell cycle control. These kinases phosphorylate threonine or serine residues that are followed by a proline residue (1-3). MAPK phosphorylates substrates with the consensus sequence PX(S/T)P and CDKs phosphorylate substrates containing the consensus sequence (S/T)PXR/K (4,5). Some signaling molecules can be regulated by phosphorylation at a specific threonine followed by an arginine or lysine at the +2 position. For example, conventional PKC isozymes phosphorylate substrates containing a serine or threonine with Arg or Lys at the -3, -2 and +2 positions (6,7). |
存放说明 | -20C |
参考图片Western blot analysis of extracts from 293 cells, untreated (-) or treated with Calyculin A #9902 (10 ng/ml, 20 min; +), using Phospho-Thr-Pro-Arg Motif [pTPR] Rabbit mAb (upper) and GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). |