Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb
货号：
13908S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 13908S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | TRAFs (TNF receptor-associated factors) are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular responses (1-3). Members of the TRAF family share a common carboxy-terminal "TRAF domain" which mediates interactions with associated proteins; many also contain amino-terminal Zinc/RING finger motifs. The first TRAFs identified, TRAF1 and TRAF2, were found by virtue of their interactions with the cytoplasmic domain of TNF-receptor 2 (TNFRII) (4). The six known TRAFs (TRAF1-6) act as adaptor proteins for a wide range of cell surface receptors and participate in the regulation of cell survival, proliferation, differentiation, and stress responses. |
| 存放说明 | -20C |
| 计算分子量 | 53 |
参考图片Western blot analysis of extracts from THP-1 cells differentiated with TPA #4174 (80 nM, overnight), untreated or LPS-treated (1 μg/ml for indicated times), using Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb (upper) or TRAF2 (C192) Antibody #4724 (lower). |
Western blot analysis of extracts from THP-1 cells differentiated with TPA #4174 (80 nM, overnight), and then either untreated (-) or transfected with poly(dA:dT) (0.004 U/ml; 7 hr; +), using Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb (upper) or TRAF2 (C192) Antibody #4724 (lower). |
