| 货号 | 5843S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-F |
| 目标/特异性 | GAD2 (D5G2) XP® Rabbit mAb recognizes endogenous levels of total GAD2 protein. |
| 使用方法 | WB(1:1000) IP (1:50) IF-F (1:50) |
| 供应商 | CST |
| 背景 | The enzyme glutamate decarboxylase (GAD) is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid (1). GAD1 (GAD67) and GAD2 (GAD65) are expressed in nervous and endocrine systems (2) and are thought to be involved in synaptic transmission (3) and insulin secretion (4), respectively. Autoantibodies against GAD2 may serve as markers for type I diabetes (5). Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2 (6). |
| 存放说明 | -20C |
| 计算分子量 | 60 |
Western blot analysis of extracts from neonatal mouse and fetal rat brain using GAD2 (D5G2) XP® Rabbit mAb. Western blot分析新生小鼠和胎大鼠大脑提取物，使用的抗体是GAD2 (D5G2) XP® Rabbit mAb 兔单抗。 | |
Confocal immunofluorescent analysis of mouse brain using GAD2 (D5G2) XP® Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA marker). 共聚焦免疫荧光分析小鼠大脑，使用GAD2 (D5G2) XP® Rabbit mAb 兔单抗（绿色）进行标记。蓝色伪彩=DRAQ5® #4084(荧光DNA标记)。 |
