| 货号 | 3892S |
| 反应种属 | Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P/F |
| 目标/特异性 | HS1 (D5A9) XP® Rabbit mAb (Rodent Specific) detects endogenous levels of total HS1 protein. This antibody does not recognize human HS1 protein. HS1 has a calculated size of 54 kDa, but has an apparent molecular weight of 80 kDa on SDS-PAGE gels. |
| 使用方法 | WB(1:1000) IP (1:200) IHC-P (1:100) F (1:100) |
| 供应商 | CST |
| 背景 | HS1 (HCLS1, LckBP1, p75) is a protein kinase substrate that is expressed only in tissues and cells of hematopoietic origin (1,2). HS1 contains four cortactin repeats and a single SH3 domain (2). This intracellular protein is phosphorylated following immune receptor activation, which promotes recruitment of HS1 to the immune synapse (3-5). Phosphorylation of HS1 is required to regulate actin dynamics and provide docking sites for many other signaling molecules, such as Vav1 and PLCγ1 (6). HS1 also plays an important role in platelet activation (7). |
| 存放说明 | -20C |
| 计算分子量 | 80 |
Immunohistochemical analysis of paraffin-embedded mouse spleen using HS1 (D5A9) XP® Rabbit mAb (Rodent Specific).免疫组织化学染色分析石蜡包埋小鼠脾脏组织。所用抗体为HS1 (D5A9) XP® Rabbit mAb (Rodent Specific)。 | |
Western blot analysis of cell extracts from Baf3, 32D, and mouse spleen using HS1 (D5A9) XP® Rabbit mAb (Rodent Specific).Western免疫印迹。用HS1 (D5A9) XP® Rabbit mAb (Rodent Specific)研究Baf3, 32D和小鼠脾脏细胞的细胞提取液。 | |
Immunohistochemical analysis of paraffin-embedded LL2 syngeneic tumor using HS1 (D5A9) XP® Rabbit mAb (Rodent Specific).免疫组织化学染色分析石蜡包埋人同系肿瘤组织。所用抗体为HS1 (D5A9) XP® Rabbit mAb (Rodent Specific)。 | |
Flow cytometric analysis of NIH/3T3 cells (red) and 32D cells (blue), using HS1 (D5A9) XP® Rabbit mAb (Rodent Specific).流式细胞仪分析NIH/3T3 细胞(红色)和32D 细胞 (蓝色)，所用抗体为HS1 (D5A9) XP® Rabbit mAb (Rodent Specific)。 |
