Keratin 17/19 (D4G2) XP® Rabbit mAb【科瑞奥博】

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Keratin 17/19 (D4G2) XP® Rabbit mAb

货号： 12434S 基本售价： 3860.0 元规格： -

产品信息

概述
货号	12434S
反应种属	Human/Mouse/Rat
来源宿主	Rabbit
应用	W/IHC-P/IF-IC
使用方法	WB(1:1000) IHC-P (1:1200) IF-IC (1:50)

性能
供应商	CST
背景	Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).
存放说明	-20C
计算分子量	48/41

参考图片

Confocal immunofluorescent analysis of keratin 17 positive HeLa (left), keratin 19 positive HCC827 (middle), and keratin 17/19 negative SK-MEL-28 (right) cells, using Keratin 17/19 (D4G2) XP^® Rabbit mAb (green). Blue pseudocolor= DRAQ5^® #4084 (fluorescent DNA dye).使用Keratin 17/19 (D4G2) XP® Rabbit mAb (绿色)对Keratin17阳性的HeLa细胞（左），Keratin19阳性的HCC827细胞（中）以及Keratin17/19阴性的SK-MEL-28细胞（右）进行激光共聚焦免疫荧光分析。蓝色假色= DRAQ5® #4084 (fluorescent DNA dye).

Immunohistochemical analysis of paraffin-embedded human ovarian carcinoma using Keratin 17/19 (D4G2) XP^® Rabbit mAb.在对照肽（左）或抗原特异性肽（右）存在的条件下使用Keratin 17/19 (D4G2) XP® Rabbit mAb对石蜡包埋的人卵巢癌组织进行激光共聚焦荧光分析。

Immunohistochemical analysis of paraffin-embedded human lung squamous cell carcinoma using Keratin 17/19 (D4G2) XP^® Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right).在对照肽（左）或抗原特异性肽（右）存在的条件下，使用Keratin 17/19 (D4G2) XP® Rabbit mAb对石蜡包埋的人肺鳞状细胞癌组织进行免疫组化分析。

Immunohistochemical analysis of paraffin-embedded keratin 17 positive HeLa cells (left), keratin 19 positive HCC827 cells (middle), and keratin 17/19 negative SK-MEL-28 cells (right), using Keratin 17/19 (D4G2) XP^® Rabbit mAb. 使用Keratin 17/19 (D4G2) XP® Rabbit mAb对石蜡包埋的Keratin17阳性的HeLa细胞（左），Keratin19阳性的HCC827细胞（中）以及Keratin17/19阴性的SK-MEL-28细胞（右）进行免疫组化分析。

Western blot analysis of extracts from various cell lines using Keratin 17/19 (D4G2) XP^® Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). 使用eratin 17/19 (D4G2) XP® Rabbit mAb (上) 或 β-Actin (D6A8) Rabbit mAb #8457 (下)对多种细胞提取物进行western blot分析。