| 货号 | 3801S |
| 反应种属 | Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IHC-P |
| 目标/特异性 | MMP-7 (D4H5) XP® Rabbit mAb detects endogenous levels of total MMP-7 protein. |
| 使用方法 | WB(1:1000) IHC-P (1:100) |
| 供应商 | CST |
| 背景 | The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5). |
| 存放说明 | -20C |
| 计算分子量 | 28, 20-22 |
Western blot analysis of extracts from COS cells, untransfected or transfected with mouse MMP-7, using MMP-7 (D4H5) XP® Rabbit mAb.使用 MMP-7 (D4H5) XP®兔单抗对未转染或者转染了小鼠MMP-7的COS细胞提取物进行western blot分析。 | |
Immunohistochemical analysis of paraffin-embedded mouse small intestine (positive, left) and mouse colon (negative, right) using MMP-7 (D4H5) XP® Rabbit mAb.石蜡包埋的小鼠小肠（阳性，左）和小鼠结肠（阴性，右）使用MMP-7 (D4H5) XP® 兔单抗进行免疫组化分析。 | |
Western blot analysis of extracts mouse intestine (MMP-7 positive), mouse colon (MMP-7 negative) and rat prostate (MMP-7 positive) tissues using MMP-7 (D4H5) XP® Rabbit mAb.小鼠肠组织（MMP-7阳性），小鼠结肠组织（MMP-7阴性）和大鼠前列腺组织（MMP-7阳性）提取物使用MMP-7 (D4H5) XP®兔单抗进行western blot分析。 |
