| 货号 | 3450S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IF-F |
| 使用方法 | WB(1:1000) IF-F (1:200) |
| 供应商 | CST |
| 背景 | Postsynaptic Density protein 95 (PSD95) is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. These family members consist of an amino-terminal variable segment followed by three PDZ domains, a SH3 domain and an inactive guanylate kinase (GK) domain. PSD95 is a scaffolding protein involved in the assembly and function of the postsynaptic density complex (1-2). PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving Stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs) (3). It is implicated in experience dependent plasticity and plays an indispensable role in learning (4). Mutations in PSD95 are associated with autism (5). |
| 存放说明 | -20C |
| 计算分子量 | 95 |
Western blot analysis of extracts from human cerebellum and rat brain using PSD95 (D27E11) XP® Rabbit mAb. Western blot分析人小脑和大鼠大脑提取物，使用的抗体是PSD95 (D27E11) XP® Rabbit mAb 兔单抗。 | |
Confocal immunofluorescent analysis of rat cerebellum and retina using PSD95 (D27E11) XP® Rabbit mAb (red) and Neurofilament-L (DA2) Mouse mAb #2835 (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). 共聚焦免疫荧光分析大鼠小脑和视网膜组织，使用PSD95 (D27E11) XP® Rabbit mAb 兔单抗（红色）和Neurofilament-L (DA2) Mouse mAb 鼠单抗#2835（绿色）进行标记。蓝色伪彩=DRAQ5® #4084(荧光DNA染料)。 |
