| 货号 | 9538S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-IC |
| 目标/特异性 | Ribosomal Protein S3 (D50G7) XP® Rabbit mAb detects endogenous levels of total ribosomal protein S3. |
| 使用方法 | WB(1:1000) IP (1:50) IF-IC (1:50) |
| 供应商 | CST |
| 背景 | Ribosomal protein S3 (rpS3) is a component of the 40S ribosomal subunit and is involved in translation. HSP90 interacts with both the amino-terminus and carboxy-terminus of rpS3, preventing its ubiquitination and degradation and thereby retaining the integrity of the ribosome (1). rpS3 has also been shown to function as an endonuclease during DNA damage repair (2,3). Furthermore, overexpression of rpS3 sensitizes lymphocytic cells to cytokine-induced apoptosis, indicating a third role for rpS3 during apoptosis (4). The functions of rpS3 during DNA damage repair and apoptosis have been mapped to two distinct domains (4). |
| 存放说明 | -20C |
| 计算分子量 | 27 |
Western blot analysis of extracts from various cell types using Ribosomal Protein S3 (D50G7) XP® Rabbit mAb. 使用Ribosomal Protein S3 (D50G7) XP® Rabbit mAb兔单抗，免疫印迹（Western Blot）分析在不同细胞系中Ribosomal Protein S3蛋白水平。 | |
Confocal immunofluorescent analysis of C6 cells using Ribosomal Protein S3 (D50G7) XP® Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). 使用Ribosomal Protein S3 (D50G7) XP® Rabbit mAb兔单抗（绿色），共聚焦免疫荧光观察Ribosomal Protein S3蛋白在C6细胞中定位。蓝色= DRAQ5® #4084 (DNA荧光染料)。 |
