| 货号 | 92427S |
| 同种亚型 | Rabbit IgG |
| 反应种属 | H Mk |
| 来源宿主 | Rabbit IgG |
| 应用 | W IP |
| 目标/特异性 | MAP4K3 (D1L4G) Rabbit mAb recognizes endogenous levels of total MAP4K3 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | The mTORC1 kinase complex is a critical regulator of cell growth (1,2). Its activity is modulated by growth factors and nutrients including amino acids (1,2). MAP4K3 is a mediator between nutrient signal and mTORC1 (1). Research studies suggest that amino acid sufficiency leads to the phosphorylation of Ser170 on MAP4K3, which activates mTORC1 (3). |
| 运输条件 | 0.75 |
| 存放说明 | -20C |
| 计算分子量 | 101 |
| 参考文献 | 1 . Findlay, G.M. et al. (2007) Biochem J 403, 13-20. 2 . Sancak, Y. et al. (2008) Science 320, 1496-501. 3 . Yan, L. et al. (2010) Mol Cell 37, 633-42. |
Western blot analysis of extracts from various cell lines using MAP4K3 (D1L4G) Rabbit mAb. |
