| 货号 | 57145S |
| 同种亚型 | Rabbit IgG |
| 反应种属 | H M Mk |
| 来源宿主 | Rabbit IgG |
| 应用 | W |
| 目标/特异性 | IMP3 (D6U2N) recognizes endogenous levels of total IMP3 protein. |
| 使用方法 | WB(1:1000) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Insulin-like growth factor-II mRNA-binding proteins (IMPs) belong to a family of zipcode-binding proteins (1,2). Three members of this family, IMP1, IMP2, and IMP3, have been identified (1,2). They contain two RNA recognition motifs, four K homology domains, and were found to function in mRNA localization, turnover, and translation control (1,2). Research studies have implicated these proteins in a variety of physiological and pathological processes, such as growth and development (3), testicular neoplasia (4), and melanocytic neoplasia (5). |
| 运输条件 | 0.75 |
| 存放说明 | -20C |
| 计算分子量 | 63 |
| 参考文献 | 1 . Nielsen, F.C. et al. (2002) J Cell Sci 115, 2087-97. 2 . Nielsen, J. et al. (2003) Biochem J 376, 383-91. 3 . Hansen, T.V. et al. (2004) Mol Cell Biol 24, 4448-64. 4 . Hammer, N.A. et al. (2005) Reproduction 130, 203-12. 5 . Pryor, J.G. et al. (2008) Mod Pathol 21, 431-7. 6 . Samanta, S. et al. (2016) Oncogene 35, 1111-21. 7 . Hoffmann, N.E. et al. (2008) Cancer 112, 1471-9. 8 . Jiang, Z. et al. (2008) Cancer 112, 2676-82. 9 . Köbel, M. et al. (2009) Mod Pathol 22, 469-75. 10 . Jeng, Y.M. et al. (2008) Hepatology 48, 1118-27. |
Western blot analysis of cell extracts from various cell lines using IMP3 (D6U2N) Rabbit mAb. |
