| 货号 | 30289S |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human\Mouse\Rat\Moneky |
| 来源宿主 | Rabbit IgG |
| 应用 | WB |
| 目标/特异性 | CNOT1 (D3V5H) Rabbit mAb recognizes endogenous levels of total CNOT1 protein. |
| 使用方法 | W |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | The evolutionarily conserved CCR4-NOT (CNOT) complex regulates mRNA metabolism in eukaryotic cells (1). This regulation occurs at different levels of mRNA synthesis and degradation, including transcription initiation, elongation, deadenylation, and degradation (1). Multiple components, including CNOT1, CNOT2, CNOT3, CNOT4, CNOT6, CNOT6L, CNOT7, CNOT8, CNOT9, and CNOT10 have been identified in this complex (2). In addition, subunit composition of this complex has been shown to vary among different tissues (3). |
| 存放说明 | -20C |
| 计算分子量 | 250, 270 |
| 参考文献 | 1 . Denis, C.L. and Chen, J. (2003) Prog Nucleic Acid Res Mol Biol 73, 221-50. 2 . Lau, N.C. et al. (2009) Biochem J 422, 443-53. 3 . Chen, C. et al. (2011) Biochem Biophys Res Commun 411, 360-4. |
Western blot analysis of extracts from MCF7, BaF3, and INS-1 cells using CNOT1 (D3V5H) Rabbit mAb. |
