货号 | 47055S |
同种亚型 | Rabbit IgG |
反应种属 | Human\Mouse\Rat |
来源宿主 | Rabbit IgG |
应用 | WB |
目标/特异性 | CAP1 (D2K3J) Rabbit mAb recognizes endogenous levels of total CAP1 protein. |
使用方法 | W |
供应商 | CST |
灵敏度 | Endogenous |
背景 | Adenylyl cyclase-associated protein 1 (CAP1) is a widely expressed actin regulatory protein that plays a role in adhesion through its interactions with talin1 and FAK (1). High CAP1 expression is associated with metastasis in hepatocellular carcinoma (2), and esophageal squamous cell carcinoma (3). Research studies also show that CAP1 expression in human epithelial ovarian cancer correlates with proliferation, histological grade, and prognosis (4). |
存放说明 | -20C |
计算分子量 | 56 |
参考文献 | 1 . Zhang, H. et al. (2013) J Biol Chem 288, 20966-77. 2 . Liu, Y. et al. (2014) Pathol Res Pract 210, 169-75. 3 . Li, M. et al. (2013) Jpn J Clin Oncol 43, 856-64. 4 . Hua, M. et al. (2015) Int J Mol Med 35, 941-9. |
Western blot analysis of extracts from various cell lines using CAP1 (D2K3J) Rabbit mAb. | |
Western blot analysis of extracts from 293T cells, mock transfected or transfected with full-length human CAP1 (hCAP1), using CAP1 (D2K3J) Rabbit mAb (upper) or Myc-Tag (71D10) Rabbit mAb #2278 (lower). |