| 货号 | 86985S |
| 同种亚型 | Rabbit IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit IgG |
| 应用 | WB, IP |
| 目标/特异性 | CD68 MultiMab™ Rabbit mAb recognizes endogenous levels of total CD68 protein. |
| 使用方法 | W IP |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | CD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1, 2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3, 4). |
| 存放说明 | -20C |
| 计算分子量 | 70-80, 130-140 |
| 参考文献 | 1 . Rabinowitz, S.S. and Gordon, S. (1991) J Exp Med 174, 827-36. 2 . Holness, C.L. and Simmons, D.L. (1993) Blood 81, 1607-13. 3 . Ramprasad, M.P. et al. (1995) Proc Natl Acad Sci U S A 92, 9580-4. 4 . Ramprasad, M.P. et al. (1996) Proc Natl Acad Sci U S A 93, 14833-8. |
Western blot analysis of extracts from THP-1, U-937, and Jurkat cells using CD68 MultiMab™ Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). | |
Immunoprecipitation of CD68 from U-937 cell extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, and lane 3 is CD68 MultiMab™ Rabbit mAb. Western blot analysis was performed using CD68 MultiMab™ Rabbit mAb. |
