货号 | 2721S |
反应种属 | Mouse |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | Wnt3a (C64F2) Rabbit mAb detects transfected Wnt3a protein in L cells and the conditioned medium from L/Wnt3a cells. |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | The Wnt family includes several secreted glycoproteins that play important roles in animal development (1). There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins (2). Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways (3). The canonical Wnt/β-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family (4). Aberrant activation of Wnt signaling pathways is involved in several types of cancers (5). |
存放说明 | -20C |
计算分子量 | 42 |
Western blot analysis of total cell lysates and conditioned medium from L cells overexpressing mouse Wnt3a, compared with parental L cells, using Wnt3a (C64F2) Rabbit mAb. 使用Wnt3a(C64F2)Rabbit mAb兔单抗,对过表达小鼠Wnt3a的L细胞和对照亲本的L细胞的全细胞裂解液和条件培养基进行western blot分析。 |