VEGF Receptor 3 (C28G5) Rabbit mAb
货号：
2638S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2638S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | VEGF Receptor 3 (C28G5) Rabbit mAb detects transfected levels of VEGFR3. This antibody does not cross-react with other family members. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Vascular endothelial growth factor receptor 3 (VEGFR3) is a 195 kDa membrane receptor tyrosine kinase. VEGF receptors are characterized by the presence of seven extracellular immunoglobulin (Ig)-like domains followed by a membrane-spanning domain and a conserved intracellular tyrosine kinase domain (1). VEGF receptor 3 expression is largely restricted to adult lymphatic endothelium and is thought to control lymphangiogenesis (1,2). Binding of VEGF-C/VEGF-D to VEGFR3 results in transphosphorylation of tyrosine residues in its intracellular domain, recruitment of signaling molecules and activation of ERK1/2 and Akt signaling cascades (1,3). |
| 存放说明 | -20C |
| 计算分子量 | 195 |
参考图片Western blot analysis of extracts from COS cells transfected with human VEGFR3 expression constructs (right) and mock transfected COS cells (left) using VEGF Receptor 3 (C28G5) Rabbit mAb.用VEGF Receptor 3 (C28G5) Rabbit mAb对转染了人的VEGFR3 （右）和空质粒（左）的COS细胞的提取物进行免疫印迹检测。 |
