货号 | 3658S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | AceCS1 (D19C6) Rabbit mAb detects endogenous levels of total cytoplasmic acetyl-CoA synthetase (AceCS1). |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | Cytoplasmic acetyl-CoA synthetase (AceCS1) catalyzes the conversion of acetate and CoA to acetyl-CoA (1, 2). Acetyl-CoA synthesized by AceCS1 is used for fatty acid and lipid biosynthesis (1, 2). Studies suggest that this enzyme is regulated by sterol regulatory element-binding proteins (2). It was also shown that this enzyme is acetylated by protein acetyltransferases in cells (3, 4). SIRT1 deacetylates this enzyme at Lys661 resulting in its activation and the increase of fatty acid synthesis (3, 4). |
存放说明 | -20C |
计算分子量 | 78 |
Western blot analysis of extracts from various cell types using AceCS1 (D19C6) Rabbit mAb. Wetern blot检测多种细胞提取物,所用抗体为AceCS1 (D19C6) Rabbit mAb兔单抗。 |