| 货号 | 3676S |
| 反应种属 | Human/Mouse/Rat/Hamster |
| 来源宿主 | Rabbit |
| 应用 | W/IHC-P/IF-IC/F |
| 目标/特异性 | Acetyl-CoA Carboxylase (C83B10) Rabbit mAb detects endogenous levels of all isoforms of acetyl-CoA carboxylase protein. |
| 使用方法 | WB(1:1000) IHC-P (1:100) F (1:400) IF-IC (1:200) |
| 供应商 | CST |
| 背景 | Acetyl-CoA carboxylase (ACC) catalyzes the pivotal step of the fatty acid synthesis pathway. The 265 kDa ACCα (ACC1) is the predominant isoform found in liver, adipocytes, and mammary gland, while the 280 kDa ACCβ (ACC2) is the major isoform in skeletal muscle and heart (1). Phosphorylation by AMPK at Ser79 or by PKA at Ser1200 inhibits the enzymatic activity of ACC (2). ACC is a potential target of anti-obesity drugs (3,4). |
| 存放说明 | -20C |
| 计算分子量 | 280 |
Flow cytometric analysis of 293 cells, using Acetyl-CoA Carboxylase (C83B10) Rb mAb (blue) compared to a nonspecific negative control antibody (red). 流式细胞检测293细胞,所用抗体为Acetyl-CoA Carboxylase (C83B10) Rabbit mAb兔单抗（蓝）, 对照为非特异性阴性抗体对照（红） | |
Western blot analysis of cell extracts from various cell lines, using Acetyl-CoA Carboxylase (C83B10) Rabbit mAb. Wetern blot检测多种细胞提取物，所用抗体为Acetyl-CoA Carboxylase (C83B10) Rabbit mAb兔单抗。 | |
Confocal immunofluorescent analysis of NIH/3T3 cells labeled with Acetyl-CoA Carboxylase (C83B10) Rabbit mAb (red). Blue pseudocolor=Draq5™ (fluorescent DNA dye). 激光共聚焦免疫荧光检测NIH/3T3细胞，所用抗体为Acetyl-CoA Carboxylase (C83B10) Rabbit mAb兔单抗（红），蓝色伪彩为DNA荧光染料(对应产品号为DRAQ5 #4084)。 | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using Acetyl-CoA Carboxylase (C83B10) Rabbit mAb. 免疫组织化学检测石蜡包埋的人乳腺癌组织，所用抗体为Acetyl-CoA Carboxylase (C83B10) Rabbit mAb兔单抗。 | |
Immunohistochemical analysis of paraffin-embedded human colon carcinoma using Acetyl-CoA Carboxylase (C83B10) Rabbit mAb. 免疫组织化学检测石蜡包埋的人结肠癌组织，所用抗体为Acetyl-CoA Carboxylase (C83B10) Rabbit mAb兔单抗。 | |
Immunohistochemical analysis of paraffin-embedded human hepatocellular carcinoma, using Acetyl-CoA Carboxylase (C83B10) Rabbit mAb. 免疫组织化学检测石蜡包埋的人肝脏细胞癌组织，所用抗体为Acetyl-CoA Carboxylase (C83B10) Rabbit mAb兔单抗。 | |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using Acetyl-CoA Carboxylase (C83B10) Rabbit mAb. 免疫组织化学检测石蜡包埋的人肺癌组织，所用抗体为Acetyl-CoA Carboxylase (C83B10) Rabbit mAb兔单抗。 | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using Acetyl-CoA Carboxylase (C83B10) Rabbit mAb in the presence of control peptide (left) or Acetyl-CoA Carboxylase (C83B10) Blocking Peptide #1062 (right). 免疫组织化学检测石蜡包埋的人乳腺癌组织，所用抗体为Acetyl-CoA Carboxylase (C83B10) Rabbit mAb兔单抗，左为对照肽，右为 Acetyl-CoA Carboxylase (C83B10) Blocking Peptide #1062 |
