ADAR1 (D7E2M) Rabbit mAb
货号:
14175S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 14175S |
反应种属 | Human/Monkey |
来源宿主 | Rabbit |
应用 | W |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Post-transcriptional processing of RNAs such as RNA editing is an important mechanism by which diversity in RNA and protein is achieved that is not otherwise encoded by the genome (1,2). The most common form of RNA editing is the conversion of adenosine (A) into inosine (I) on double stranded RNA by the adenosine deaminase acting on RNA (ADAR) family of proteins (1-3). Since inosine base pairs with cytidine, it is interpreted as a guanosine by the splicing and translational machinery leading to alteration in the protein sequence, as well as splicing isoforms being generated (1,4-6). A-to-I editing can also influence RNA sequence recognition by RNA binding proteins and non-coding RNA, such as miRNAs, affecting subsequent RNA processing, stability, and protein expression levels (2). |
存放说明 | -20C |
计算分子量 | 110, 150 |
参考图片Western blot analysis of extracts from HeLa cells, untreated (-) or treated with hIFN-α1 #8927 (+), and Hep G2 and Vero cells, using ADAR1 (D7E2M) Rabbit mAb. |