| 货号 | 12035S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | ALDH1A1 (D4R9V) Rabbit mAb recognizes endogenous levels of total ALDH1A1 protein. |
| 使用方法 | WB(1:1000) IP (1:100) |
| 供应商 | CST |
| 背景 | The aldehyde dehydrogenase family is a large group of enzymes that oxidize aldehydes formed through metabolic processes to their carboxylic acids (1). ALDH1A1 is a liver cytosolic isoform of acetaldehyde dehydrogenase and is involved in the major pathway of alcohol metabolism along with alcohol dehydrogenase (2). ALDH1A1 is also known as retinal dehydrogenase 1 and is involved in retinol metabolism, converting retinol to retinoic acid (3). Recent studies suggest that control of retinoid signaling through ALDH1A1 may influence hematopoietic stem cell differentiation (4). There has been recent interest in ALDH1 isoforms as predictive biomarkers in disease. Several studies have suggested that ALDH1A1 is a potential marker for cancer stem cells and chemoresistance in several tumor types, such as melanoma (5), lung cancer (6), glioblastoma (7). |
| 存放说明 | -20C |
| 计算分子量 | 55 |
Western blot analysis of extracts from Hep 3B and Hep G2 cells using ALDH1A1 (D4R9V) Rabbit mAb. Western blot 检测Hep 3B和Hep G2细胞系提取物，使用抗体为ALDH1A1 (D4R9V) Rabbit mAb兔单抗。 |
