货号 | 2171S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Mouse |
应用 | W/IP |
目标/特异性 | Alix (3A9) Mouse mAb detects endogenous levels of total Alix protein. |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | Alix, a phylogenetically conserved cytosolic scaffold protein, contains an N-terminal Bro1 domain, a coiled-coil region and a C-terminal proline-rich domain (1,2). Originally identified as an ALG-2 (apoptosis-linked gene 2)-interacting protein involved in programmed cell death (3,4), Alix also regulates many other cellular processes, such as endocytic membrane trafficking and cell adhesion through interactions with ESCRT (endosomal sorting complex required for transport) proteins, endophilins, and CIN85 (Cbl-interacting protein of 85 kDa) (5,6). |
存放说明 | -20C |
计算分子量 | 95 |
Western blot analysis of cell extracts from various cell types using Alix (3A9) Mouse mAb. Western免疫印迹。用Alix (3A9) Mouse mAb 鼠单抗研究各种细胞系的细胞提取液。 |