ALPP (3E5C7) Mouse mAb
货号：
8681S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 8681S |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | ALPP (3E5C7) Mouse mAb recognizes endogenous levels of total ALPP protein. This antibody may cross-react with a protein of unknown origin at ~140 kDa in some cell lines. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Mammalian alkaline phosphatases (APs) are highly conserved zinc-containing allosteric enzymes that are able to hydrolyze and transphosphorylate a wide range of compounds (1). There are four known human alkaline phosphatase isozymes: TNAP (tissue-nonspecific; bone/liver/kidney), ALPP (placental), ALPP2 (germ cell), and ALPI (intestinal) (2). Placental alkaline phosphatase (ALPP) is bound to the plasma membrane via a glycosyl-phosphatidylinositol (GPI) anchor (3). It is expressed primarily in the placenta (4) and may be involved in transplacental IgG transport (5). ALPP has been found to be overexpressed on the surface of several different types of solid tumor cells (6) and elevated serum concentrations of ALPP and ALPP-like enzymes has been found to be associated with ovarian, cervical, and testicular cancer (7). |
| 存放说明 | -20C |
| 计算分子量 | 70 |
参考图片Western blot analysis of extracts from A-431 cells and human placental tissue using ALPP (3E5C7) Mouse mAb. 使用ALPP (3E5C7)Mouse mAb对A-431细胞和人胎盘组织提取物进行western blot分析。 |
