| 货号 | 14528S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | Aromatase is a member of the cytochrome P450 superfamily of enzymes, which are monooxygenases that catalyze reactions involved in drug metabolism and cholesterol and steroid synthesis (1,2). Aromatase is responsible for the conversion of testosterone into 17-β estradiol (2). Aromatase is mainly expressed in the brain (3), ovaries (4), and placenta (5). Aromatase plays an important role in development of the central nervous system during ontogenesis (6,7), gonadal development, and sex differentiation (8,9). Research studies have suggested that inhibition of aromatase may be an effective therapeutic strategy for postmenopausal breast cancers that are estrogen receptor positive (6,10). Mutations in the corresponding aromatase gene are associated with cases of aromatase excess syndrome (AEXS) and aromatase deficiency (AROD) disorders (11-14). |
| 存放说明 | -20C |
| 计算分子量 | 50 |
Western blot analysis of extracts from mouse, rat, and human placenta tissue using Aromatase (D5Q2Y) Rabbit mAb. | |
Immunoprecipitation of aromatase from mouse placenta extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or Aromatase (D5Q2Y) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using Aromatase (D5Q2Y) Rabbit mAb and Mouse Anti-rabbit IgG (Conformation Specific) (L27A9) mAb (HRP Conjugate) #5127. |
