Axl (C89E7) Rabbit mAb【科瑞奥博】

产品中心

当前位置：首页>产品中心

Axl (C89E7) Rabbit mAb

货号： 8661S 基本售价： 3360.0 元规格： -

产品信息

概述
货号	8661S
反应种属	Human/Monkey
来源宿主	Rabbit
应用	W/IP/IHC-P/IF-IC/F
目标/特异性	Axl (C89E7) Rabbit mAb detects endogenous levels of total Axl protein. The antibody does not cross-react with related proteins.
使用方法	WB(1:1000) IP (1:50) IHC-P (1:300) F (1:100) IF-IC (1:100)

性能
供应商	CST
背景	Axl, Sky, and Mer are three members of a receptor tyrosine kinase (RTK) family that share a conserved intracellular tyrosine kinase domain and an extracellular domain similar to those seen in cell adhesion molecules. These RTKs bind the vitamin K-dependent protein growth-arrest-specific 6 (Gas6), which is structurally related to the protein S anticoagulation factor (1). Upon binding to its receptor, Gas6 activates phosphatidylinositol 3-kinase (PI3K) and its downstream targets Akt and S6K, as well as NF-κB (2,3). A large body of evidence supports a role for Gas6/Axl signaling in cell growth and survival in normal and cancer cells (4).
存放说明	-20C
计算分子量	138

参考图片

Immunohistochemical analysis of paraffin-embedded cell pellets, NCI-H1299 (left) or Jurkat (right), using Axl (C89E7) Rabbit mAb.免疫组织化学方法检测石蜡包埋的NCI-H1299细胞球（左图）和Jurkat细胞球（右图），使用的抗体为Axl (C89E7) Rabbit mAb.

Immunohistochemical analysis of paraffin-embedded breast carcinoma using Axl (C89E7) Rabbit mAb. Note staining of infiltrating cells.免疫组织化学方法检测石蜡包埋的乳腺癌组织，使用的抗体为Axl (C89E7) Rabbit mAb. 注意浸润细胞染色。

Confocal immunofluorescent analysis of DU 145 (left) and HCC827 (right) cells using Axl (C89E7) Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).激光共聚焦免疫荧光方法检测DU 145细胞(左图)和HCC827细胞(右图)，使用的抗体为Axl (C89E7) Rabbit mAb (绿色)。蓝色伪彩色是DNA荧光染料，产品信息为DRAQ5® #4084.

Immunohistochemical analysis of paraffin-embedded metastatic lung carcinoma using Axl (C89E7) Rabbit mAb.免疫组织化学方法检测石蜡包埋的转移性肺癌组织，使用的抗体为Axl (C89E7) Rabbit mAb.

Western blot analysis of extracts from various cell lines using Axl (C89E7) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).Western blot方法检测多个细胞系的提取物，使用的抗体为Axl (C89E7) Rabbit mAb (上图)和 β-Actin (D6A8) Rabbit mAb #8457 (下图).

Flow cytometric analysis of Jurkat cells (blue) and DU145 cells (green) using Axl (C89E7H4) Rabbit mAb.流式细胞术分析Jurkat细胞(蓝色)和DU145细胞（绿色），使用的抗体为Axl (C89E7H4) Rabbit mAb.