BiP (C50B12) Rabbit mAb【科瑞奥博】

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BiP (C50B12) Rabbit mAb

货号： 3177S 基本售价： 3360.0 元规格： -

产品信息

概述
货号	3177S
反应种属	Human/Mouse
来源宿主	Rabbit
应用	W/IHC-P/IHC-F/F
目标/特异性	BiP (C50B12) Rabbit mAb detects endogenous levels of total BiP protein.
使用方法	WB(1:1000) IHC-P (1:200) F (1:200) IHC-F (1:200)

性能
供应商	CST
背景	Secretory and transmembrane proteins are synthesized on polysomes and translocated into the endoplasmic reticulum (ER). Inside the ER, these proteins are often modified by disulfide bond formation, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including BiP. BiP was identified as an immunoglobulin heavy chain binding protein in pre-B cells (1,2). It was also found to be induced at the protein level by glucose starvation (3). When protein folding is disturbed inside ER, BiP synthesis is increased. Subsequently, BiP binds to misfolded proteins to prevent them from forming aggregates and assists in proper refolding (4).
存放说明	-20C
计算分子量	78

参考图片

Immunohistochemical analysis of paraffin-embedded human breast carcinoma using BiP (C50B12) Rabbit mAb in the presence of control peptide (left) or BiP Blocking Peptide #1084 (right).

对石蜡包埋的人乳腺癌使用BiP (C50B12) Rabbit mAb兔单抗进行免疫组织化学分析，其中左图为存在对照肽，右图为存在BiP抗体封闭肽#1084。

Western blot analysis of extracts from various cell lines using BiP (C50B12) Rabbit mAb.

对多个细胞系使用BiP (C50B12) Rabbit mAb兔单抗进行Western blot分析。

Immunohistochemical analysis of paraffin-embedded human glioblastoma using BiP (C50B12) Rabbit mAb.

对石蜡包埋的人胶质细胞瘤使用BiP (C50B12) Rabbit mAb兔单抗进行免疫组化分析。

Immunohistochemical analysis of paraffin-embedded human colon carcinoma using BiP (C50B12) Rabbit mAb.

对石蜡包埋的人结肠癌使用BiP (C50B12) Rabbit mAb兔单抗进行免疫组化分析。

Immunohistochemical analysis of paraffin-embedded human hepatocellular carcinoma using BiP (C50B12) Rabbit mAb.

对石蜡包埋的人肝细胞癌使用BiP (C50B12) Rabbit mAb兔单抗进行免疫组化分析。

Immunohistochemical analysis of frozen SKOV-3 xenograft using BiP (C50B12) Rabbit mAb.

对冰冻SKOV-3异源移植物使用BiP (C50B12) Rabbit mAb兔单抗进行免疫组化分析。

Flow cytometric analysis of A204 cells using BiP (C50B12) Rabbit mAb (blue) compared to concentration-matched Rabbit (DA1E) mAb IgG XP^® Isotype Control #3900 (red). Anti-rabbit IgG (H+L), F(ab)₂ Fragment (Alexa Fluor^® 488 Conjugate) #4412 was used as a secondary antibody.