BMP4 (6B7) Mouse mAb
货号:
4680S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 4680S |
反应种属 | Human |
来源宿主 | Mouse |
应用 | W |
目标/特异性 | BMP4 (6B7) Mouse mAb detects transfected levels of total BMP4 protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation (1,2). BMPs belongs to the TGF-β superfamily, playing many diverse functions during development (3). BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems (3,4). |
存放说明 | -20C |
计算分子量 | 47 |
参考图片Western blot analysis of extracts from COS cells, either mock transfected or transfected with a human BMP4 construct, using BMP4 (6B7) Mouse mAb.使用BMP4 (6B7) Mouse mAb对转染或未转染人BMP4质粒的COS细胞提取物进行westernblot分析。 |