| 货号 | 8968S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | CASK (D24B12) Rabbit mAb recognizes endogenous levels of total CASK protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | CASK is an adaptor protein with a calcium/calmodulin-dependent protein kinase domain, an SH3 domain, a guanylate kinase homology domain (GUK), and a PDZ domain. CASK links transmembrane proteins to the cytoskeleton and signaling molecules. In particular, CASK binds to neurexin to stabilize pre- and post-synaptic structures (1). While most CASK protein (~80%) is cytoplasmic, a portion of the protein enters the nucleus, where it acts as a transcriptional coactivator (2). Transgenic mice with CASK insertional mutations die within 24 hours of birth (3). |
| 存放说明 | -20C |
| 计算分子量 | 105 |
Western blot analysis of extracts from various tissues using CASK (D24B12) Rabbit mAb. Western blot分析多个组织提取物，使用的抗体是CASK (D24B12) Rabbit mAb 兔单抗。 |
