Caspase-3 (3G2) Mouse mAb
货号:
9668S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 9668S |
反应种属 | Human |
来源宿主 | Mouse |
应用 | W |
目标/特异性 | Caspase-3 (3G2) Mouse mAb detects endogenous levels of full length (35 kDa) and the large fragment (17/19 kDa) of caspase-3 resulting from cleavage at aspartic acid 175. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP) (1). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position (2). |
存放说明 | -20C |
计算分子量 | 17, 19, 35 |