Caspase-7 (C7) Mouse mAb (Human Specific)
货号：
9494S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 9494S |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | Caspase-7 (C7) Mouse mAb (Human Specific) detects endogenous levels of caspase-7 proform as well as the 30 and 20 kDa cleaved fragments. This antibody does not cross-react with other caspases. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis (2-4). Caspase-7 is an effector caspase (along with caspase-2 and -3), meaning that it cleaves essential cellular machinery rather than activating other caspases (5-8). Caspase-7 is cleaved by many enzymes, including caspases-3, -6, -8, -9 and granzyme B (1,4,5). Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase, or PARP (2,4). |
| 存放说明 | -20C |
| 计算分子量 | 20, 30, 35 |
参考图片Western blot analysis of extract from Jurkat cells, untreated or etoposide-treated, using Caspase-7 (C7) Mouse mAb (Human Specific). 采用Caspase-7 (C7) Mouse mAb (Human Specific) 鼠单抗对未处理或 etoposide 处理的 Jurkat 细胞的细胞提取物进行 western blot 分析。 |
