Caspase-9 (C9) Mouse mAb
货号：
9508S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 9508S |
| 反应种属 | Human/Mouse/Rat/Hamster/Monkey |
| 来源宿主 | Mouse |
| 应用 | W |
| 目标/特异性 | Caspase-9 (C9) Antibody detects endogenous levels of the pro form of caspase-9 as well as cleaved fragments. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family (1,2). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Additional cleavage occurs at Asp330 producing a p37 subunit that can serve to amplify the apoptotic response (3-6). Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to initiate a caspase cascade, which leads to apoptosis (7-10). |
| 存放说明 | -20C |
| 计算分子量 | 47 /37/35 (H). 51 /39/37 (R,M). |
