CDCP1 (D8M5K) Rabbit mAb
货号：
12327S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 12327S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | CDCP1 (D8M5K) Rabbit mAb recognizes endogenous levels of total CDCP1 protein. This antibody recognizes an epitope in the extracellular domain of CDCP1. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | CDCP1 (CUB domain containing protein, SIMA135) is a putative stem cell marker that has been shown in research studies to be highly expressed in some human cancer cells and in both typical and atypical (cancerous) colons (1). Expression of CDCP1 may be epigenetically regulated, as methylation of promoter CpG sequences results in decreased CDCP1 expression (2). The corresponding CDCP1 gene encodes a glycoprotein that acts as a complex, multidomain transmembrane antigen. Three CUB domains in its extracellular region are possibly involved in cell adhesion or extracellular matrix interaction (1,3). Src-family kinases may phosphorylate CDCP1 at five tyrosine residues within its cytoplasmic domain to provide a potential binding site for SH2 domain-containing proteins (3). CDCP1 is a putative marker for hematopoietic stem cells (4,5). |
| 存放说明 | -20C |
| 计算分子量 | 140 |
参考图片Western blot analysis of extracts from various cell lines using CDCP1 (D8M5K) Rabbit mAb.Western blot分析多种细胞系提取物，使用的抗体是CDCP1 (D8M5K) Rabbit mAb。 |
