| 货号 | 12306S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P/IF-IC |
| 目标/特异性 | CDX2 (D11D10) Rabbit mAb recognizes endogenous levels of total CDX2 protein. |
| 使用方法 | WB(1:1000) IP (1:100) IHC-P (1:2000) IF-IC (1:50) |
| 供应商 | CST |
| 背景 | CDX2, a homeobox domain-containing transcription factor, is a master regulator of the trophoectoderm, the layer that gives rise to extra-embryonic tissues in mammalian development (1). CDX2 is also involved in intestinal development (2), and gain of expression or loss of expression has been associated with various human malignancies such as Barret Esophagus (3) and colorectal cancer (4,5). Mouse embryonic stem cells deficient in CDX2 display limited hematopoietic progenitor development and altered Hox gene expression (6), pointing to a role for CDX2 in Hox gene regulation. CDX2 is also implicated in the aberrant expression of Hox genes in human AML cell lines (7). |
| 存放说明 | -20C |
| 计算分子量 | 38 |
Confocal immunofluorescent analysis of DLD-1 (positive, left) and HeLa (negative, right) cells using CDX2 (D11D10) Rabbit mAb (green). Actin filaments were labeled with DY-554 phalloidin (red). 使用CDX2 (D11D10)Rabbit mAb（绿色）对DLD-1 (阳性, 左) 和 HeLa (阴性，右)进行激光共聚焦免疫荧光分析。肌动蛋白丝用DY-554 phalloidin 标记（红色）。 | |
Immunohistochemical analysis of paraffin-embedded human colon using CDX2 (D11D10) Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right). 在存在对照肽段（左）或抗原特异性肽段（右）的条件下对石蜡包埋的人结肠癌组织，使用CDX2 (D11D10)Rabbit mAb兔单抗进行免疫组化分析。 | |
Immunohistochemical analysis of paraffin-embedded human colon carcinoma using CDX2 (D11D10) Rabbit mAb. 使用CDX2 (D11D10)Rabbit mAb对石蜡包埋的人结肠癌组织进行免疫组化分析。 | |
Western blot analysis of extracts from various cell lines using CDX2 (D11D10) Rabbit mAb. HeLa extracts show negative or extremely low expression as expected. 使用CDX2 (D11D10)Rabbit mAb兔单抗对多种细胞提取物进行western blot分析。HeLa细胞提取物中CDX2阴性或表达极低。 |
