| 货号 | 8431S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | CISH (D4C10) Rabbit mAb recognizes endogenous levels of total CISH protein. |
| 使用方法 | WB(1:1000) IP (1:100) |
| 供应商 | CST |
| 背景 | The suppressor of cytokine signaling (SOCS) family members are negative regulators of cytokine signal transduction that inhibit the Jak/Stat pathway (1-3). The SOCS family consists of at least 8 members including the originally identified cytokine-inducible SH2-containing protein (CIS1), as well as SOCS1-7. Each SOCS family member contains a central SH2 domain and a conserved carboxy-terminal motif designated as the SOCS box. These proteins are important regulators of cytokine signaling, proliferation, differentiation, and immune responses.SOCS (细胞因子信号抑制剂)家族成员能负调控细胞因子信号传导而抑制 Jak/Stat信号通路(1-3)。 |
| 存放说明 | -20C |
| 计算分子量 | 32, 37 |
Western blot analysis of extracts from NK-92 cells, untreated (-) or treated (+) with Human Interleukin-2 (hIL-2) #8907 (10 ng/ml, overnight), using CISH (D4C10) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).Western免疫印迹。用CISH (D4C10) Rabbit mAb(上图) 和β-Actin (D6A8) Rabbit mAb #8457 (下图) 研究未经处理(-)的和经hIL-2 #8907 (10 ng/ml)处理过夜(+)的NK-92细胞系的细胞提取液。 | |
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing full-length human CISH (hCISH, +), using CISH (D4C10) Rabbit mAb.Western免疫印迹。用CISH (D4C10) Rabbit mAb研究对照转染(-)和转染了表达人全长CISH质粒(hCISH, +)的293T细胞的细胞提取液。 |
