货号 | 42143S |
反应种属 | Human |
来源宿主 | Rabbit IgG |
应用 | W/IP |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | Clusterin (CLU, apolipoprotein J) is a multifunctional glycoprotein that is expressed ubiquitously in most tissues. Clusterin functions as a secreted chaperone protein that interacts with and stabilizes stress-induced proteins to prevent their precipitation (1,2). Research studies show that clusterin plays a protective role in Alzheimer’s disease by sequestering amyloid β(1-40) peptides to form long-lived, stable complexes, which prevents amyloid fibril formation (3-5). |
存放说明 | -20C |
计算分子量 | 32-42, 65, 75 |
Western blot analysis of extracts from concentrated, serum-free culture medium of MCF7 and U-118 MG cells using Clusterin (D4B6P) Rabbit mAb. | |
Western blot analysis of extracts from MCF7 and Huh7 cells using Clusterin (D4B6P) Rabbit mAb. | |
Immunoprecipitation of clusterin from MCF7 cell extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, and lane 3 is Clusterin (D4B6P) Rabbit mAb. Western blot analysis was performed using Clusterin (D4B6P) Rabbit mAb and Mouse Anti-rabbit IgG (Conformation Specific) (L27A9) mAb #3678. |