| 货号 | 14368S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P |
| 使用方法 | WB(1:1000) IP (1:50) IHC-P (1:1000) |
| 供应商 | CST |
| 背景 | Catechol-O-methyltransferase (COMT) is an intracellular enzyme that catalyzes the O-methylation and inactivation of catecholamine neurotransmitters and hormones, including dopamine, epinephrine, and norepinephrine (1). Two distinct COMT proteins are generated from separate promoters in cells, including a 28 kDa, membrane-bound protein (mb-COMT), and a soluble protein (s-COMT) of 24 kDa (2,3). The soluble s-COMT is the predominant form of COMT found in peripheral organs, while the mb-COMT protein is more abundant in the central nervous system (4,5). |
| 存放说明 | -20C |
| 计算分子量 | 24, 28 |
Western blot analysis of extracts from K-562 and SH-SY5Y cell lines and human prostate using COMT (D4N6M) Rabbit mAb. | |
Immunoprecipitation of COMT from K-562 cell extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or COMT (D4N6M) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using COMT (D4N6M) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded normal human liver using COMT (D4N6M) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human prostate carcinoma using COMT (D4N6M) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded normal human breast using COMT (D4N6M) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded normal human kidney using COMT (D4N6M) Rabbit mAb in the presence of control peptide (left) and antigen-specific peptide (right). |
