CYLD (D6O5O) Rabbit mAb
货号：
12797S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 12797S |
| 反应种属 | Human/Mouse/Rat/Hamster/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | CYLD (D6O5O) Rabbit mAb recognizes endogenous levels of total CYLD protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | CYLD is a cytoplasmic deubiquitinating enzyme encoded by a tumor suppressor gene altered in individuals diagnosed with cylindromatosis, a genetic condition characterized by benign tumors of skin appendages (1,2). Functional CYLD deubiquitinase regulates inflammation and cell proliferation by down regulating NF-κB signaling through removal of ubiquitin chains from several NF-κB pathway proteins (3,4). CYLD is a negative regulator of proximal events in Wnt/β-catenin signaling and is a critical regulator of natural killer T cell development (5,6). The transcription factor Snail can inhibit CYLD expression, resulting in melanoma cell proliferation (7). |
| 存放说明 | -20C |
| 计算分子量 | 109 |
参考图片Western blot analysis of extracts from various cell lines using CYLD (D6O5O) Rabbit mAb. Western blot检测多种细胞提取物。 |
