CYP3A4 (D9U6N) Rabbit mAb
货号:
13384S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 13384S |
反应种属 | Human/Mouse |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | CYP3A4 (D9U6N) Rabbit mAb recognizes endogenous levels of total CYP3A4 protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Cytochrome P450, subfamily 3A, polypeptide 4 (CYP3A4) is a mono-oxygenase enzyme (1) found in the endoplasmic reticulum membrane of liver and prostate microsomes. It is an important enzyme in drug metabolism; it catalyzes phase I oxidation reactions in approximately 50% of drugs in the modern market, as well as steroids, fatty acids, and some carcinogens (2). It is also involved in steroid and cholesterol synthesis (3,4). Expression of CYP3A4 can be induced by glucocorticoids, carcinogens, pesticides, and drugs, which can lead to drug interactions and toxicity (5). |
存放说明 | -20C |
计算分子量 | 50 |
参考图片Western blot analysis of extract from various human tissues using CYP3A4 (D9U6N) Rabbit mAb (upper) and GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). Antibody specifically detects CYP3A4 only in human liver, as expected. 使用CYP3A4 (D9U6N) Rabbit mAb兔单抗 (upper) and GAPDH (D16H11) XP® Rabbit mAb 兔单抗#5174 (lower)对多种人类组织提取物进行western blot分析。如预期,抗体只会特异性检测人肝脏组织中的CYP3A4。 |