货号 | 5362S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | Dicer (D38E7) Rabbit mAb detects endogenous levels of total Dicer protein. |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3 UTR of the target mRNA (3). |
存放说明 | -20C |
计算分子量 | 220 |
Western blot analysis of extracts from MCF7 and 293 cells using Dicer (D38E7) Rabbit mAb. 使用Dicer (D38E7) Rabbit mAb,免疫印迹(Western Blotting)分析MCF7和293细胞系裂解物。 |