DNA Ligase IV (D5N5N) Rabbit mAb
货号:
14649S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 14649S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | DNA double-strand breaks (DSBs) are potentially hazardous lesions that can be induced by ionizing radiation (IR), radiomimetic chemicals, or DNA replication inhibitors. Cells detect and repair DSBs through two distinct but partly overlapping signaling pathways, nonhomologous end joining (NHEJ) and homologous recombination (HR). DNA repair through the HR pathway is restricted to S and G2 phases of the cell cycle, while NHEJ can occur during any cell cycle phase. Defects in both pathways have been associated with human disease, including cancer (1). |
存放说明 | -20C |
计算分子量 | 100 |
参考图片Western blot analysis of extracts from various cell lines using DNA Ligase IV (D5N5N) Rabbit mAb. |