| 货号 | 2294S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P/F |
| 目标/特异性 | DRAK2 (33D7) Rabbit mAb detects endogenous levels of total DRAK2 protein. |
| 使用方法 | WB(1:1000) IP (1:50) IHC-P (1:50) F (1:200) |
| 供应商 | CST |
| 背景 | DRAK2 (DAP kinase related apoptosis inducing protein kinase 2) is a member of the novel DAP (death associated protein) pro-apoptotic kinase family (1). Overexpression of DRAK2 in NIH/3T3 cells induces morphological changes associated with apoptosis, which are likely to occur in a p53-dependent manner (1,2). DRAK2 is preferentially expressed in lymphoid tissues and regulates the TCR activation threshold during thymocyte selection (3). Indeed, T cells from DRAK2(-/-) mice exhibit enhanced sensitivity to T cell receptor-mediated stimulation and have a reduced requirement for co-stimulation (4). |
| 存放说明 | -20C |
| 计算分子量 | 43 |
Western blot analysis of total cell lysates from BaF3 and mouse thymocytes, using DRAK2 (33D7) Rabbit mAb. Western blot 检测BaF3细胞和小鼠胸腺细胞总裂解液提取物，使用抗体为DRAK2 (33D7) Rabbit mAb兔单抗。 | |
Flow cytometric analysis of BaF3 cells, using DRAK2 (33D7) Rabbit mAb (blue) compared to a nonspecific negative control antibody (red). 流式细胞术检测BaF3细胞，使用的抗体为 DRAK2 (33D7) Rabbit mAb （蓝色）兔单抗，用一个非特异性负对照抗体（红色）作为对照。 | |
Immunohistochemical analysis of paraffin-embedded mouse thymus, using DRAK2 (33D7) Rabbit mAb. 免疫组织化学分析石蜡包埋的小鼠胸腺，使用抗体为 DRAK2 (33D7) Rabbit mAb兔单抗。 |
